The Body Borg is synonymous with Metabolic X Syndrome, which began with the dawn of agriculture.
Ori Hofmekler, author of “The Warrior Diet” points out that cereals and starches are slave food for subduing the masses into a placid, bovine, slow-witted intelligence suitable for hard labor. www.warriordiet.com/ We can see why this is when we consider the “receptor resistance” factor induced by cereal consumption. Cereals may be food for the masses but they do not make for sustainable culture, evolving populations or individuating sovereigns. They instead lead to metabolic X syndrome and the depletion of societal resources in coping with compounding dysfunction and disease. That disease is big business in Borg society is an understatement.
During the feudal and industrial ages cereals made for a malleable servile slave class, that would even lay down their lives for their rulers. But now in the information age, a high carbohydrate diet is a cognition killer when combined with modern lifestyle challenges such as the lack of exercise and the various agents of inflammation: EMFs, radiation, toxins, processed food, high-carb, low-protein diets, common allergens like casein and gluten, dysbiosis, pathogens, stress, lack of sleep, sick building syndrome etc… Most polyunsaturated vegetable oils like safflower, sunflower, corn, peanut and soy, are high in linoleic acid, an omega-6 essential fatty acid that the body converts into the pro-inflammatory arachidonic acid. These same oils contain almost no omega-3’s, which soothe inflammation. Our prehistoric ancestors ate a diet with an omega-6 to omega-3 ratio of 1:1, while our current ratio is between 10:1 and 25:1. This has profound effects for cell energy production as mentioned in the pieces on cardiolipin below (*See July and the Omega-3 list in August).
Although agricultural production of cereals allowed more people to survive over the millennia than otherwise would have, it is not “quantity” of people that we need, but “quality.” Through our learned cultural choices we are now hitting the metabolic wall with regards to the “sustainable quality” of human health and well-being. The plentiful supply of cheap cereal carbohydrates over the last 10 thousand years has resulted in a dysmetabolic pandemic that is inherited epigenetically and through cultural habit…changing the very nature of the “human,” and directly causing the diseases of aging and degeneration.
Extreme fluctuation of insulin levels results from a diet high in refined carbohydrate foods such as sugar, sweetened soft drinks and white bread. These are absorbed quickly from the intestines into the blood stream causing a sudden rise in blood glucose levels. Rapidly absorbed carbohydrates are said to have a “high glycemic index.” In order to stimulate the cells to absorb this sudden glucose load, the pancreas responds by releasing larger than normal quantities of insulin. The excessive amount of serum insulin precipitates a sudden fall in blood glucose, and within a couple of hours this level becomes very low. The consequent slump in energy stimulates craving for more high glycemic foods causing the blood glucose to rise dramatically once more, thus perpetuating the cycle of wildly fluctuating glucose and insulin levels.
Insulin is the primary hormone that controls how the body's cells absorb, use and store nutrients and energy. The amount of insulin the pancreas produces is in relation to the amount of carbohydrates eat. When extra carbs are eaten the excess beyond immediate fuel needs is stored as fat for burning in the future should extra energy be required. So if you eat fewer carbohydrates less insulin is produce and less fat is stored. When we eat carbohydrates in excess of our immediate fuel needs the pancreas must produce higher amounts of insulin, which overloads the insulin receptors and so they become numb or insulin resistant. When blood glucose is high, fat burning (lipolysis) is inhibited by insulin, thus ingestion of glucose rich foods is the primary factor in precipitating obesity. Also in the domesticated diet we are not getting a rich supply of the phytochemicals and antioxidants that reduce many of the pathological mechanisms that underlie obesity, diabetes and metabolic syndrome.
Adipose tissue is an important endocrine organ that secretes numerous protein hormones, including leptin. The fat cell derived hormone Leptin (Greek leptos meaning thin) plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism. That the human leptin system is not specifically adapted to a cereal-based diet is one of the main reasons for the obesity epidemic and metabolic syndrome in general. The diseases of affluence involve increased insulin and leptin resistance which interferes with the cells hormonal feeding and energy metabolism regulation. Lectins are sugar-binding proteins found in cereals that play a role in biological recognition phenomena involving cells and proteins. Cereal lectins can cause leptin resistance either indirectly, through effects on leptin metabolism, and/or directly, through binding to the leptin or the leptin receptor, thereby affecting their function.
Leptin and insulin resistance are central to the cascade of metabolic X syndrome—high blood sugar, pathogens, reduction in oxygen, reduced energy generation, low cell voltage, sticky blood, sluggish lymph, lowered immunity, inflammation, glycation, exhausted antioxidant systems, overworked organs, insufficient energy for detoxification, aging of cells, fatigue and run away appetite and cravings as the cells are neither being fed or cleaned properly. This condition underlies all degenerative disease and provides the perfect terrain for infectious disease. Quality of life and Presence are greatly reduced as we fail to generate the energy needed to “pull ourselves together” into an integrated whole. As we restore our energy metabolism and integrate our cosmic an-atom-y we tap into vast inner resources of cosmic integration.
Cinnamon is a convenient and delicious method of raising insulin sensitivity. Researchers found that taking 1 tsp of cinnamon with meals resulted in a 50% reduction in blood sugar within 90 minutes, compared to controls. Cinnamon lowers blood sugar by activating phosphorylation of the insulin receptor, which then draws the sugar and nutrient transporters from the inner cell to the cell membrane where they pull the sugar and nutrients into the cell. In other words, the glucose transporter Glut4 is transported from cellular vesicles to the cell surface, where it then can mediate the transport of glucose into the cell. Insulin resistance prevents phosphorylation, while the better your phosphorylation the greater hormonal intelligence and the younger, thinner you’ll be.
Although insulin mainly works in muscle, fat and the liver, this hormone also exerts profound effects on many other body tissues. Besides regulating the cellular glucose metabolism, amino acids and fatty acids, insulin and insulin-like growth factor also activates and inactivates enzymes and directly affects certain genetic processes including protein synthesis, gene expression and cell growth and differentiation.
Insulin apparently exerts its glucose-lowering effects by stimulating glucose uptake in tissues such as skeletal muscle, suppressing fatty acid release from fat (adipose) tissue, and inhibiting production of glucose by the liver. It should be noted here that there are some tissues that do not require insulin for efficient uptake of glucose: important examples are the brain and the liver. This is because these cells don't use GLUT4 for importing glucose, but rather, another transporter that is not insulin-dependent. Liver, brain, and Red blood cells lack the insulin sensitive GLUT4. GLUT3 is a high affinity glucose transporter used in tissues highly dependent on glucose such as the brain. GLUT1 is responsible for the basic supply of glucose to the cells, red blood cells and the endothelial cells of the brain. GLUT1 appears to be the primary isoform for glucose transport through blood/tissue barriers including the retina, brain, placenta, testes and cerebrospinal fluid. The rate of transport is highly dependent on blood glucose levels.
The liver has a central role in glucose homeostasis because it extracts glucose from the bloodstream in times of plenty, and synthesizes glucose in times of need. Glucose metabolism throughout the body is coordinated by the brain in that the liver receives control signals from the hypothalamus, an area of the brain known to detect and integrate metabolic signals. Insulin acts on specialized ion channels, called KATP channels, in the hypothalamus to control glucose production. These channels, which lie in the outer membranes of hypothalamic neurons release potassium ions from cells in response to a drop in ATP. Decreased levels of ATP in response to falling glucose levels open the KATP channels allowing potassium ions to leave the cell, resulting in membrane hyperpolarization and reduced membrane excitability, which dampens its electrical activity.
Another downside of cereal consumption is the toxin acrylamide, which is by-product of fried, toasted and caramelized carbohydrates. The food toxin acrylamide is a carcinogen, that fragments DNA and generates free radicals. Turmeric’s anti-inflammatory effects reduce the damage done by acrylamide. Turmeric also activates a genetic switch that generates more endogenous antioxidants. If we took “cinnamon, turmeric, papain/bromelain, kelp, spirulina” capsules with our meals…this along with the adoption of a more raw Paleolithic diet would greatly reduce the myriad symptoms of Metabolic Syndrome X. While transitioning however bread addicts can get away with some traditional Danish rye bread...which uses lacto-fermentation rather than yeast. I find uncolored Pumpernickel to be somewhat non-inflammatory.
The sovereign can avoid grains by eating crackers and breads made with sprouted non-cereal grains and seeds, that are technically raw by being “cooked” in a dehydrator. Non-cereal foods that can be made into flour for flat or leavened breads include: amaranth, quinoa, buckwheat, wattleseed, kañiwa, cattail pollen and roots, breadnut, lambsquarters seed, chestnuts, hazelnuts, almonds, acorns, coconut, green pea, Bunya pine nuts, peanuts, poppy seed, pumpkin, sesame, sunflower, Ginkgo, Mango seed. Chia/flaxseed/hemp crackers etc...made in a dehydrator may be a fine bread substitute.
A cereal-free hunter-gatherer diet promoted significantly higher insulin sensitivity, lower diastolic blood pressure and lower C-reactive protein, the levels of which rise in response to inflammation. The “Fall of Man” is due to the aberrated, deranged, acidifying and toxifying effects of the common Western diet. To build a strong sovereign body we must eliminate hyperinsulemia and eradicate the imbalanced terrain that encourages all manner of pathogens and parasites. We arrive at resistance to oxidative stress and inflammation by rectifying the toxic sludge of the blood—through increasing our leptin/insulin sensitivity and engaging in regular aerobic exercise to increase the glucose transporters and build mitochondria numbers. In this way we can quickly get sugar out of the blood and into the cells to burn as “life energy” without having to squirrel the excess away in the fat cells, risk glycating our protein structures, or without it being a fertile medium for pathogens. Regulating our energy metabolism is fundamental to genetic strength, longevity, immunity and stress resistance.
We can reverse aging, restore mitochondria to a more youthful expression and control our destiny to a marked degree with regular exercise and healthy eating.
Dangerous Grains: Why Gluten Cereal Grains May Be Hazardous To Your Health by James Braly M.D. and Ron Hoggan M.A.
Advanced Nutrition and Human Metabolism, by Sareen S. Gropper, Jack L. Smith, James L. Groff
Monday, September 19, 2011
Wednesday, August 17, 2011
THE OMEGAS
The most abundant omega-3 fatty acids are Eicosapentaenoic acid (20:5n-3 EPA), Docosahexaenoic acid (22:6n-3 DHA), and Docosapentaenoic acid (22:5n-3 DPA), in that order. Eggs contain some DHA, especially those from chickens fed on algae, fish and Omega-3 containing plants like purlsane or moringa. Poultry feed plentiful purslane, insects and lots of fresh green grass, supplemented with fresh and dried figs, barley, and corn can have an Omega-6 to Omega-3 ratio of 1:3. “Grass” fed lamb and organ meats such as liver and brains, are abundant sources, too. Nuts and seeds such as walnuts, flax-seed and hemp contain omega-3s, though the body has to convert these plant sources from ALA to DHA. The short-chain plant source omega-3 known as ALA delivers lesser heart benefits. The body partially converts alpha-linolenic acid (ALA) to the two omega-3’s EPA (15%) and DHA (5%), but there are many things that interfere with this conversion such as: high omega-6 linoleic acid (LA) from vegetable oils, saturated transfats, alcohol, certain drugs, diabetes, certain races used to high seafood diet and deficiencies of vitamins B3, B6, C, and zinc.
RATFISH OIL: This deepsea shark liver oil contains Omega 3, 4, 6, 7, 9 and 11 in an advantageous distribution to the body. Of all the omega-3 sources the synergistic effects of Ratfish oil may be the fastest route to reestablishing mitochondria energy production through the normalization of Ca2+ concentrations, building of cardiolipin concentrations in the mitochondrial membrane, and as a powerful antioxidant to prevent disruption of the electron transport chain. Ratfish oil heals the effects of the toxic halogens on the pineal and thyroid—thyroxin being needed for cardiolipin production.
Ratfish oil is such a powerful antioxidant that it helps to revive the thyroid from the destructive effects of the halides chlorine, fluorine and bromine…thereby raising Thyroxin enough to maintain cardiolipin levels in the mitochondrial membranes. The introduction of chlorine and fluoride into our lives since the WW2 is one of the greatest factors in the destabilization our immune system and instigated conditions ripe for cancer, fungi, tooth decay and candida, by further reducing iodine levels in bodies that are already iodine deficient. Thus we see the chronically fatigued, diseased and low conscious state of the Borg is very much a culturally instigated phenomena. Ratfish oil is sold online by a Norwegian company ratfishoil.com. An approximation of Ratfish oil’s attributes can be achieved by using krill oil, spirulina, Vitamin K2 and sunlight.
KRILL OIL: Together with plankton, krill make up the largest biomass on earth. During feeding season a blue whale eats up to 8,000 pounds of krill each day. Supplemental Krill oil is better than fish oil for it is loaded with its own antioxidants such as the carotenoid Astaxanthin, which is at least ten times more effective than beta-carotene and may be as much as five hundred times more powerful than Vitamin E. The hydroxyl and carbonyl groups in Astaxanthin help to anchor this molecule to the cell membrane thus protecting the cell membrane and the mitochondrial membrane from lipid. Krill oil also contains vitamins A and E. Antarctic Pure Krill Oil is so stable that it is said last for two years at room temperature. The omega-3’s in fish oil are in the less-beneficial triglyceride form, while krill oil omega-3’s are in the form of phospholipids, which are little liposome packages that deliver the fatty acids directly to your cells. Studies have also shown that the Omega-3 bound phospholipids are far less prone to oxidations than Omega-3 in traditional triglyceride forms. The most predominant phospholipid in pure krill oil is phosphatidyl choline, which is partially composed of choline needed for brain development, learning and memory. It can also be of benefit to the function of the eyes, brain and the nervous system because Antaxanthin does cross the blood-brain barrier. Not all krill oil is equal, Dr. Mercola’s Antarctic Pure Krill Oil and krilldoctor.com looks high integrity. Dr. Ray Sahelian endorses Physician Formulas Krill oil.
FISH OIL: Fish oil supplements contain a mix of the long-chain omega-3s docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). However DHA is superior to EPA in improving mitochondrial function and suppressing inflammation. As with other omega 3 sources fish oil increases mitochondrial phospholipid unsaturation of cardiolipin, resulting in an increase in ROS and initiating apoptotic cascade of programmed cell death that helps prevent cells with damaged DNA from proliferating out of control. Both dietary flaxseed oil and fish oil increased the expression of mitochondrial acetyl-CoA binding protein and phosphatidic acid mass, but only fish oil increased cardiolipin mass. The DHA and EPA in fish oil are more easily oxidized than the unsaturated ALA fatty acids in vegetable oil and so high quality, and fresh fish sources are best, specifically those that are low in mercury. Do not eat shark, swordfish, king mackerel or tilefish as these fish typically contain high levels of mercury. The combination of cod liver oil and olive oil may have greater benefits to platelet membranes than either taken separately.
OMEGA-3 RDA: Fish Oil/Omega-3 recommended rate: A 180-pound man take 4.5 g EPA+DHA per day. 1 pound of fish per week works out to about 1.5 g omega-3 fats per day. Fish with the most amount of Omega-3 are: 100gm King salmon - 2,300mg, Albacore tuna - 1,800mg, Black cod - 1,600mg, Silver salmon - 1,300mg, Sockeye salmon - 1,200mg. Shellfish have relatively few omega-3s, compared with fish. The higher a marine animal is on the food chain the more diversity of fatty acids it contains. In some marine mammal and fish species, omega-3 fatty acids may represent 15 -45% of all fatty acids present. Generally avoid cooking or exposing omega-3’s to heat, sun or air.
MICROALGAE: Marine microalgae, or phytoplankton is perhaps the most nutritious food that exists, containing every nutrient required by the human body, in near-perfect ratios. Its deep color comes from a rainbow of solar-collecting pigments: chlorophyll (green), phycocyanin (blue) and carotenoids (orange). As primary producers algae are at the bottom of the food chain, in fact fish get their DHA from algae. Algae are rich sources of DHA, but contain little EPA, therefore Spirulina, Blue-Green Algae and Chlorella may be the best food for building up high integrity cardiolipin, for they are also loaded with a large variety of antioxidants, phytonutrients, protein, beta-carotene, GLA, B-Vitamins including Vitamin B12, minerals, chlorophyll, lutein, thiamine, sulfolipids, glyco-lipids, superoxide dismutase, lipoic acid, enzymes, RNA, and DNA. Spirulina is 50% vegetable protein with a digestibility coefficient is 95.1% and unlike high uric acid forming protein from animal products that contribute to osteoporosis and can cause kidney damage. Algae have the powerful ability to help detoxify the body, suppress candida yeast and bad bacteria like e-coli, while increasing beneficial flora as much as four times normal, which helps you resist diseases. DHA manufactured using microalgae is vegetarian, eco-friendly and sustainable. You'll need at least 1 teaspoon every day, which is the nutritional equivalent of 3 servings of dark green leafy vegetables!. Cyanotech uses deep sea water for their spirulina cultivation so it will be radiation free. 4 lbs for $86.95 from www.nutritiongeeks.com. Cyanotecmh also isolate Astaxanthin in the product BioAstin®.
DHA OMEGA-3: Docosahexaenoic acid is the most abundant omega-3 fatty acid in the brain and retina. Fifty percent of the weight of a neuron's plasma membrane is composed of DHA. DHA comprises 40% of the polyunsaturated fatty acids (PUFAs) in the brain and 60% of the PUFAs in the retina. In chemical structure DHA omega-3 is a carboxylic acid with a 22-carbon chain and six cis double bonds. DHA is a major fatty acid very high metabolic tissue such as sperm, brain phospholipids and in the retina. DHA (docosahexaenoic acid) and EPA (eicosapentaenoic acid) are the two specific omega 3 fatty acids found in such cold water fish as salmon, cod and mackerel. DHA and EPA are also the two substances the body uses most readily. ALA (alpha-linolenic acid) is another omega 3 fatty acid, and it is found in plant oils such as flaxseed (linseed) and perilla, with lower amounts in walnut, canola and soy. It is converted by your body to DHA and EPA once you consume it. These substances are inserted in cell membranes throughout the body, where cellular machinery converts them into substances which prevent abnormal clotting, reduce inflammation, and relax blood vessels. Although we can do much in our own lives to reinstate our mitochondrial energy production such as eating less grains and more salmon—it is through changing the energy metabolism of women who are to bear children and ensuring that they have adequate levels of DHA fatty acid that we will make the quickest advances in regaining species sanity, integrity and spirituality. Basically cell memebrains/membranes have to be made smart in order to uptake fuel and nutrients and excrete toxins and send messages. If they are not smart enough to do these functions then metabolism and consciousness start heading towards death. DHA makes brain cell membranes flexible, and optimizes electrical signaling, and quickens and intensifies brain processing. Essential Fatty Acids are the prime structural components of brain cell membranes and are also an important part of the enzymes within cell membranes that allow the membranes to transport valuable nutrients in and out of the cells.
DPA OMEGA-3: Docosapetaenoic acid which contains 22.5 carbon bonds and works synergistically with the other types of Omega 3’s. About a third of the long-chain Omega 3 fatty acids circulating in human blood is attributable to DPA, concentrating mostly in the heart, brain and liver. In the 1970’s a Danish researcher, Jorn Dyerberg, wondered why Greenland
Eskimos had such a low incidence of heart attacks when their diet was so high in fat. DPA along with the other omega 3 fatty acids may be a major contributing factor to the overall good cardiovascular health of the Eskimos as DPA is said to be ten times more effective than EPA in healing damaged blood vessels. DPA may have a structural role in cell membrane organization, preserves synaptic connections, prevents cognitive decline and reduces reduce inflammation. Seal Oil contains all three components of Omega 3; EPA, DPA, DHA and in the same proportions that are found naturally in the human body. While most fish oils lack DPA seal oil can provide up to ten times the DPA as fish oils. Some ringed seal specimens, the percent composition of all omega-3 fatty acids exceeds 35%. In the body supplemented DPA is converted into EPA and vice versa, but supplemented EPA and DPA do not seem to be converted into DHA.
OMEGA-3 PLANT SOURCES: Plants and nuts contain mostly contain mostly the short-chain ALA omega-3. The body does a poor job of converting short-chain omega-3s to long-chain to the long-chain omega-3 fatty acids — DHA and EPA. Things such as stress, gender, genetics, diet, disease, toxins, balance of fats, caffeine, alcohol, smoking, sugar and freshness of the product all can hinder our ability to convert alpha linolenic acid (LNA ) omega 3 to DHA and EPA forms.
Dark leafy greens including moringa leaf contain a small amount of ALA omega-3. Purslane contains the highest amount of Omega 3 fatty acids of any leafy green plant. Seeds and oil of Hemp, Flax, Borage, and Chia which is a mint plant. Sacha Inchi Oil, Camu camu oil. I intuit the fatty acids in the oil of Camu-Camu (Myrciaria dubia) we will probably find to be one of the best oils for reinstating mitochondria function. Camu Camu Fruit Powder, and leaves also provide maximum antioxidant power to protect the mitochondria. Cold pressed black raspberry seeds contain 85% essential fatty acids, 30% of which is Omega-3. Argan oil from Moroccon argan kernels are rich in vitamin E and essential fatty acids, phenols and phenolic acid, carotenes, squalene, and more resistant to oxidation than olive oil. Avocado Seed Oil also contains omega-3 and raises levels of soluble collagen thereby rebuilding collagen in the skin. Mustard seeds, like all seeds of the Brassica family have high levels of omega-3 (6–11%). a very high source of selenium, niacin, as well as a good source of iron, calcium, zinc, selenium, manganese, magnesium, and the amino acid tryptophan.
KIWIFRUIT: Consider that when trying to increase Omega-3 in the body that it is the actual % of ALA compared to the other fatty acids that we are trying to achieve with the ultimate goal to returning to the Paleolithic ideal of 1:1 Omega-3: Omega-6. The queen of all the Omega-3 sources appears to be kiwifruit seed oil for it contains 62.9% alpha-linolenic acid. www.osel.co.nz/
PERILLA OIL: (Perilla frutescens) shiso a member of the mint family. Perilla contains multiple anti-inflammatory flavones, present in both the leaf and the seed. The seeds of the Perilla plant are a good source of oil, at approximately 40% oil content, 54-64% of which is omega-3 fatty acid alpha-linolenic acid (ALA) which is converted into DHA and EPA by the body. By comparison, flax seed oils have ranged as low as 46% omega-3 fatty acids. Oleic acid (omega-9) is also present in perilla oil. Perilla is one of the best oils to achieve balance in the fatty acids because of its unusually high content of omega 3 fatty acids, and the absence of mercury risk from fish sources. The very highest sources of vegan Omega-3 appear to be Kiwifruit and Perilla oils...but to really catalyze ATP production it looks like Omega-5 from Pomegranate seed oil is the master booster.
OMEGA-5: Pomegranate seed oil (Punica granatum) is one of the only plant sources of omega-5 conjugated fatty acids and it contains an abundant amount of punicic acid 18:3 (n-5), i.e. it has three conjugated double bonds. The genus name, Punica is named after the Phoenicians, Pomegranate fruit has rounded hexagonal shape. The punicic acid found pomegranate seed oil and has been called a "super CLA" or Conjugated Linolenic Acid, which supports the immune system. Pomegranate contains many phytochemicals with antioxidant action, such as ellagic acid which has anti-cancer, anti-arthritis and anti-inflammatory activity. The pomegranate seed oil carries ORAC values which top the list of the ORAC chart. Omega-5 or Punicic Acid, an 18-carbon fatty acid possessing three double bonds, that is one of the most potent antioxidants known to modern science, in fact six times more potent than grape seed extract. Pomegranate seed oil also has strong chemopreventative, anti-inflammatory and anti-microbial effects. It improved digestive health, and greater hormonal balance, and stimulates keratinocyte proliferation, which promotes regeneration of the skin. As a CLA Omega-5 helps repair damaged cells, and also controls and regulates glucose transport at the cell membrane level, making it particularly useful for individuals with insulin resistance. Because of its effect on repairing cell membranes and therefore ATP production it has a significant effect on the human electromagnetic field, increasing it by as much as much as tenfold (40 to 50 feet). This looks like the best place for Pomegranate, Perilla and Blackseed oil. http://stores.ebay.com/islamichalalstore
OMEGA-7: Macadamia nut oil is the main commercially available source of the omega-7, containing approximately 22% palmitoleic acid. Its oil is unique among edible sources in that monounsaturated fatty acids are the predominant component (about 80%), while the palmitoleic acid provides high oxidative stability making it a desirable ingredient in skincare. Other sources of omega-7 include the Chilean hazel (Gevuina) and Sea Buckthorn oil. Omega-7 helps stabilize cell membranes and is effective in protecting the skin from damage while also lowering cholesterol and triglycerides.
Friday, August 12, 2011
MITO MEDITATION
Sit in the easy chair position with a bolster under your knees (or in bed). Left hand on the heart, right hand on the solar plexus. Drop the muscles at the back of your tongue and do the inner smile, engage slow gentle deep belly breathing. Get the sense you are floating weightless and pull your minds eye into your inner core. Now sense the 100 trillion cells making up your body and feel into the mitochondria within the cells. Direct gratitude and love, a deep gentle, sweetness, welcoming encouragement and unconditional blessing (beneficence) into your mitochondria…thanking them for producing the fuel that fires up your existence and lights the way. The more you direct your focus into your energy producing plants the greater they will come forth in response, to produce more energy, more clarity and greater efficiency…thereby undoing stress, dysfunction and aging at its source.
That which is loved grows stronger…this is the mothering that “derepresses” suspended epigenetic expression. The fundamental axiom of Life is that it is environment created and creates environment. We can love ourselves into incarnating a greater degree of Self by the quality of attention we give to our cells. You have to be unconditionally happy and bliss-filled to make healthy love to your mitochondria and in return, they will take you to the moon and back. Turning the light around to appreciate the organelle that drives our spaceship is the flip of the switch into hyperdrive. The body is a starship, the mitochondria are its engine room. When you tune into your engine room with conscious loving intent and gratitude (especially first thing in the morning before rising from bed) you green light yourself and liberate your energy stores for the day. This self-loving attention is contagious, and so others imbibe self-care and empowerment from our switched on self-loving bodymind.
It is interesting that if you have discombobulated your nervous system with stress (cortisol) or food that is exhausting for the body to process it is very hard to focus on the mitochondria or to conjure up gratitude. This points to the need for a stress reduction and clean-living lifestyle in order to manifest maximum ATP/light. We need high ATP levels and coherent light to generate Gamma wave frequency in the prefrontal lobes. It takes the supreme focus of Gamma wave to “touch” the mitochondria with love, hence liberate the focused attention needed for learning and memory. We literally re-member our Self through focusing the light of our attention inward.
Remember the mitochondria hold a different set of genes based on the female line, so by green lighting them, you support the epigenetic expression of genes which may have been repressed/depressed during the struggle of females within an oppositional and anti-Eros culture. During Mitochondrial meditation you can feel more activity in the right side of the brain, thus we can lift the lid placed on our feminine intelligence (intuition, empathy, synthesis, wholism, psi, visions, gnosis etc...). Freeing our feminine receptive energy from the shame of Eve and fully showing up as a force of sanity, balance, care and will to pull the human race back from the brink of destruction.
The Inner Arts are the principle form of bonding whereby we attain a deeper relationship with our Self and hence a deeper relationship with the cosmos. By establishing this primary connection we are less likely to be pulled off track into unhealthy entropic relationships that dis-integrate our integrity and waste our time and energy. The more we establish a Gamma wave meditative connection to our mitochondria, the more we build our sovereign core. Stick with the mitochondria meditation first, as you need to get a Uraeus (Gamma wave) connection to your power-plants. In the beginning this communication/communion with your mitochondria is definitely an "exercise," and as you gain success with the contact, you can feel the body do a jump or jolt, like moving through threshold levels of self-recognition or self-remembering.
Initially self-love takes an enormous effort in concentrating Presence, but the results are immediate. As well as sending gratitude to your mitochondria spend some time sending gratitude to your liver as well, for the colossal processing service it does for you. Send gratitude to any other part of the body that is troubling you to bring it back into the wholeness of the integrated starship. The Merkaba lightship is accessed through the gamma connection with the mitochondria, so build that up first.
Link the gamma wave Uraeus with the proton vectors of the mitochondrial membranes and we materialize through stargates to greater incarnation in this dimension by jumping to higher octaves in energy valence. The Mitochondria Meditation is best done first thing in the morning prior to the mask of the daily personality descending, which locks us into a habitual level of energy/consciousness associated with our past conditioning. This may be the secret to the transfiguration of the body, holy communion and the divine life.
The Mito Meditation...of gratitude toward the mitochondria is one of the best methods of installing abundance programming. Because abundance comes from appreciation for that which we already have. There must be apriori satisfaction in order to get out of deprivation consciousness, poverty, fight/flight and criminal gain. Abundance is "built" by rising beyond the neediness level and raising the body's energy and frequency to the radiant-giving level...through which gnosis, genius, synchronicity, enterprise, adventure, true fun and joy occur. Once we are in "right HUman relationship" to the universe...abundance just falls into play from the coordinating resonant energy of our own cellular gratitude and appreciation (depth).
Intra-Stellar Contact
"I was in an hour long Mitochondria Meditation session. I had non-stop jumps. I am so excited with my initial contact. In my session, I was completely naked and I was floating in the Universe. I felt the beauty of my body. I felt the breeze, the moon light, I landed on the moon and fooled around with rocks and looked down at the earth... When I visualized the cells and sent lights to the mitochondria, all the body/mind armor are disintegrated. I no longer need the usual stuff to protect me!!!!!!!!!! I am at the quantum level, I am with the Universe. The prohibition of Eros is being blasted away by my lighted mitochondria.” Debbie M
Monday, July 18, 2011
ONE COUNTRY, ONE PEOPLE, ONE GLOBE, ONE PROBLEM
CARDIOLIPIN ~The Heart of the Matter
The term Cardiolipin (CL) literally means heart fat, because it was first discovered in cow hearts and is one of the most abundant lipids in heart tissue.
Cardiolipin (CL) is a structurally unique dimeric phospholipid found almost exclusively in the inner mitochondrial membrane where it is essential for the optimal function of numerous enzymes that are involved in mitochondrial energy metabolism that produces. In mammalian cells, but also in plant cells, the negatively charged phospholipid cardiolipin (CL) is essential for the optimal function of numerous enzymes that are involved in the respiratory functions of energy metabolism to form of ATP by oxidizing food molecules. In addition to its role in maintaining membrane potential and architecture, CL is known to provide essential structural and functional support to several proteins involved in mitochondrial bioenergetics.
CL is required for the proper structure and activity of several mitochondrial respiratory chain complexes involved in the oxidative generation of ATP and has been proposed to participate directly in proton conduction through cytochrome bc1 and prevent osmotic instability and uncoupling at higher respiration rates. In addition to its role in mitochondrial bioenergetics, CL also plays an essential role in cell apoptosis, mitochondrial biogenesis and the assembly of complex respiratory enzymes. The functional importance of CL probably arises from its unique ability to interact with proteins and its role in maintaining inner membrane fluidity, osmotic stability and may help to make the inner membrane impermeable. Cardiolipin stabilizes supercomplexes of the respiratory chain, thus mitochondria require a constant level of cardiolipin to function correctly. Even subtle deficits in mitochondrial function can cause weakness, fatigue and cognitive difficulties.
Cardiolipin comprises 10% of the total phospholipids of the heart muscles and 25% of the phospholipids of the inner mitochondrial membrane, plus it is a minor component of the lipoproteins in human blood plasma where it is believed to function as an anti-coagulant. It also occurs on the outer membrane of mitochondria at the 4% level, at which point its hexagonal shape connects the outer with the inner membrane, where it interacts with a large number of mitochondrial proteins having a profound influence on vital cell processes. Most importantly this interaction activates enzymes involved in oxidative phosphorylation and photo-phosphorylation, which result in ATP production.
Cardiolipin is also bound to DNA maintaining mitochondrial DNA stability and is involved in the folding of mitochondrial proteins. Thus cardiolipin has a role in gene expression, enzyme systems, cell division, energy metabolism and membrane transport. Cardiolipin is also involved in cholesterol movement from the outer to the inner membrane and thus key to the production of steroid hormones. Testosterone increases basal metabolic rate and may be considered a fat-burning hormone. One of the reasons testosterone raises the metabolic rate is because it is involved in polyunsaturated fatty acid biosynthesis, and significantly modifies the cardiolipin function more toward stimulating oxidative phosphorylation (oxy phos).
Cardiolipin contains four fatty acids, in differing quantities in different cell types depending on their specific energy needs in various regions of the body. In tissues with high respiration rates, such as heart, CL can account for 25% of the phospholipids in the inner-mitochondrial membrane. In most animal tissues cardiolipin is composed of 18-carbon fatty acids, typically linoleic acid, in testis however it contains mainly palmitic acid, while brain cardiolipin has a variety of fatty acids including arachidonic acid and DHA. The omega-9 fatty acid Oleic acid was one of the most prominent components; the chief source of oleic acid in foods is olive oil. The oleic acid protecting phytochemical components of olive leaf may be one of the reasons why olive leaf increases mitochondrial function and reduces the pathogen load, by helping to shift the body over to oxygen burning from a more anaerobic-fermentation state. Linoleic acid also appears to be a component of the cardiolipin in the liver.
CARDIOLIPIN ENERGY AND ORDER
The complexity of the human species and our potential for awareness requires a certain perfect precision in our material make-up which we ourselves may not yet be fully cognizant of. Life uses energy to self-organize toward ever-greater energy, synergy and complexity. Life’s evolutionary building of energy and greater order is in a sense the opposite of chaos and entropy. Through anthropogenic eyes we can see that hominids started traveling down the route towards metabolic energy crisis, chaos and disorder when cereal agriculture shifted our essential fatty acid consumption more toward Omega-6 dominance at the expense of Omega-3. The 10,000 years of cereal consumption and consequent breakdown in our cellular energy generation lowers the moral and spiritual consciousness of the species, allowing all manner of violent, criminal, predatory, parasitic, tyrannical and anti-life thought, behavior and processes to occur.
In exploring Borg Metabolic X syndrome I went looking for why there is a decline in oxy phos ATP generation and consequent reliance on aerobic and anaerobic glycolysis to generate ATP. When fats are heated, hydrogenated, made into transfats or when omega-6 from cereals is eaten in excess of omega-3 this destroys the structure and function of the cell membranes and mitochondrial membranes. When these misshapen fats are incorporated into the cell membrane it becomes saturated, rigid, less flexible and unable to function properly. This in combination with the free radicals from chronic stress, industrial food, toxins, pollution leads to systemic cellular inflammation, insulin resistance and the breakdown of the intake mechanisms for getting both glucose into the cell and pyruvate into the mitochondria.
When cell voltage falls as a consequence of inadequate ATP production this throws off active ATP dependent transport, uptake receptors, membrane potential, function of ion gates (channels), pH differentials, nutrition and detoxification of the cell, and reduces the energy available for cell maintenance and repair. As the cell loses its metabolic intelligence the organism experiences an associated loss of consciousness, communication and sentience, whereby it falls out of bliss connection with Gaia and descends into an ever-deepening depleted or “needy” state.
Besides all the other factors in biological systems decline that leads to the fallen Borg condition, we must focus intently on the decreased quality of fatty acids and their disproportion in the diet as being instrumental to species degeneration; because of the consequent loss of Cardiolipin (L4CL) in the inner membrane of the mitochondria interferes with pyruvate uptake leading to the decline in oxy phos ATP generation. Vibrant cellular mitochondria respiration is the basis for good health. Depending on their energy demand organs are affected to differing degrees by impaired of mitochondrial function; the heart, the skeletal muscle cells, the brain and retina therefore show a much more pronounced response to mitochondrial insufficiency.
Thus we can say that Borg Metabolic X and its associated energy decline has a lot to do with cardiolipin loss in the inner membrane of the mitochondria. Insufficiency of this vital component and the reduced ATP underlie all degenerative disease and the mental-emotional-social decline of the species into undifferentiated “closed” Borg consciousness. The humanization process of specificity, complexity, depth, integration and “openness” are reduced due to this energy slump...even as human culture itself slowly evolves and technological progress powers ahead. The veneer of civilization thus props up the underlying metabolic-spiritual decline of the species, even as it is falling apart at its power-generating source. This loss of energy is ultimately dehumanizing both of the individual body, mind and soul, but also greatly undermines the overall progress of human evolution itself.
The symptoms of the Borg Metabolic X syndrome include: demineralization, HPA-hyperactivation, burnt-out adrenals, reduced thyroid, increased insulin resistance and collapsed mitochondria energy generation. This crippled condition forms the basis to the spiritual castration of populations into the uncreative slave populations (the sleep of sheep). It doesn’t take much imagination to see how the reduction in cellular energy production and the consequent loss of consciousness and Will to Live allows human predators and parasites to run riot over the globe. The runaway psychopathic control grid uses malevolent Nazi techniques to dehumanize society into the slave machine population. Once the ever-widening control grid has been set up over multiple generations via social-control techniques (a lot of which were developed by the Nazis in WWII) then we have to find ways to exit or transcend the cultural mind in order to save our soul, our bloodline and anything of true value in human life.
We see clearly how the net of species decline is set when we look at how hypothyroidism and low thyroid (thyroxin) levels ties into lower cellular respiration and the flip over to glycolysis associated with cancer, heart disease, diabetes, neuropathy and aging. The lower activity of the pyruvate carrier in mitochondria from aging and hypothyroidism may be ascribed to changes in the lipid domain surrounding the carrier molecule in the mitochondrial membrane. And how by reinstating our “normal” mitochondrial levels of Cardiolipin fatty acid we can increase our oxy phos ATP production, and in so doing increase cell voltage and thus reestablish the high energy levels needed for health and sovereignty. Plus raising the DHA levels of Cardiolipin also reinstates the healthy cell death (apoptosis) necessary to avoid cancerous growth. With inferior cardiolipin both the life and death processes of the cell are undermined.
We can observe how loss of thyroid function leads to the loss of pyruvate conversion into ATP by studying what happens with excessive thyroid activity. When rats are made hyperthyroid, hormone-mediated changes in the cardiolipin composition of the mitochondrial membranes occurs; in particular, the negatively charged phospholipids such as cardiolipin and phosphatidylserine were found to increase by more than 50%. Plus minor alterations were found in the pattern of fatty acids with an increase in the ratio 20:4 to 18:2 molar. These changes in the mitochondrial phospholipid composition alter the kinetic parameters of pyruvate transport in mitochondria. This in turn amplifies the activity of the pyruvate carrier and stimulates pyruvate-dependent oxygen uptake by 35-40% in mitochondria, essentially greatly raising cell metabolism. (Yet to be substantiated: if pyruvate cannot freely enter into the mitochondria due to inferior mitochondrial membranes, this must mean that glucose levels would build up in the cytosol…stimulating the enzymes for glycolysis…thus transferring the fuel for oxy phos ATP production over the anaerobic fermentation method that produces only 2 ATP, compared to the larger amount of 36-38 ATP by oxy phos, wasting 95% of the potential glucose energy.)
Studies indicate that rat cardiac mitochondrial oxygen consumption and the enzymatic activity of cytochrome oxidase decreased as the quantity of cardiolipin (L4CL) was reduced when the fatty acid composition of the diet was changed. A loss of CL content and alterations in its composition, along with CL peroxidation have been associated with mitochondrial dysfunction in a variety of pathological conditions, including ischemia, hypothyroidism, diabetes, aging, and heart disease. It is clear therefore that changes in the quantity, content and structure of CL occur in mitochondrial dysfunction forming the basis of metabolic dysfunction and degenerative disease.
Heart mitochondria from hypothyroid rats translocate pyruvate much more slowly and have a parallel decrease of the rate of pyruvate-dependent oxygen uptake from normal rats. IN FROM HYPOTHYROID RATS THE HEART MITOCHONDRIAL FATTY ACID PATTERN IN THE MITOCHONDRIAL MEMBRANES WAS ALTERED, SUGGESTING THAT CHANGES IN THE LIPID ENVIRONMENT WHICH SURROUNDS THE PYRUVATE CARRIER MOLECULE IN THE MITOCHONDRIAL MEMBRANE RESULTS IN THE DECREASED ACTIVITY OF THE PYRUVATE TRANSLOCATOR.
Mitochondrial dysfunction can occur when the amount of CL declines due to enhanced CL degradation (e.g., hydrolysis by endogenous phospholipases) or by the reduced synthesis of new CL, as a result of impaired enzyme function or the unavailability of CL precursors. Aging also reduces the rate of pyruvate transport in mitochondria (38%) and is associated with the parallel lowering in the rate of pyruvate-dependent oxygen uptake. This loss of efficiency can be attributed to the fact that heart aging significantly alters the mitochondrial lipid composition. These changes include total cholesterol increases (43%), the phospholipids decrease (15%) and the cholesterol/phospholipid molar ratio increases (68%). Among phospholipids, it is cardiolipin that shows the greatest alteration (28% decrease in aged rats), perhaps because of its extra vulnerability to oxidation.
Cardiolipin may be particularly susceptible to free radical peroxidation because of the abundance of double bonds in its structure and its close association with respiratory chain proteins, which are known to be a major source of reactive oxygen species (ROS) in the mitochondria. Oxidative injury of mitochondria is widely believed to play an important role in the mitochondrial decay and dysfunction seen in aging and may contribute to an age-associated decline in CL. Loss of CL and composition alterations due to aging was closely associated with decreased activity of the mitochondrial phosphate transporter, pyruvate carrier, adenine nucleotide transporter, cytochrome oxidase, and the Acetyl-l-carnitine transporter.
Acetyl-l-carnitine’s major function in the body is to help transport long-chain fatty acids so they can be used for eventual energy production. It also helps maintain levels of coenzyme A (acetyl-CoA), which is essential for a number of metabolic reactions. Acetyl-l-carnitine also has neuroprotective, cardioprotective, cytoprotective, antioxidant and anti-apoptotic activity. Vitamin C is required for the synthesis of the carnitine that is needed for this transport of fat into mitochondria, for conversion to energy. Lifelong intake of powerful antioxidants both supplemental and in the diet will help preserve cardiolipin levels and maintain energy generation as we age. *Remember, simply taking increased Omega-3 into a highly oxidizing, inflammatory, high blood sugar/glycating, fermenting, demineralized, hypothyroid/low-voltage body will only add high quality fuel to the process of putrification and decay.
Supplementation with L-carnitine and α-lipoic acid reduces CL losses and the age-related increase in free radicals (hydrogen peroxide) in heart mitochondria. Interestingly, acetyl-carnitine effects are limited to preservation of "normal" CL levels, and may involve improved mitochondrial fatty acid import and a preservation of cellular high-energy phosphate content needed for ATP. Not surprisingly treatment of aged rats with acetyl-L-carnitine reversed the age-associated decline in cardiolipin content. As the changes in cardiolipin content were correlated with changes in rates of pyruvate transport and oxidation, it is thought that acetyl-L-carnitine reverses the age-related decline in the mitochondrial pyruvate metabolism by restoring the normal cardiolipin content.
Acetyl L carnitine stimulates the electron transport as does caffeine and Coenzyme Q10. Kelp or iodine is necessary to keep up the thyroxin levels needed for Cardiolipin synthesis, for the thyroid hormone is a major regulator of mitochondrial biogenesis, respiratory function and lipid metabolism and has been shown to directly modulate CL content by influencing the activity of CL biosynthesis enzymes. Thyroxin induces new CL synthesis by increasing the activities of CL synthase and phosphatidylglycerol phosphate synthase, and promotes the remodeling of CL. Conversely, low thyroxin or hypothyroidism decreases the activities of CL synthase resulting in a significant loss of CL content and the functioning of CL-dependent protein, which in turn are restored by treatment with thyroid hormone. Thus the loss of CL and associated mitochondrial protein function in the aged, hypothyroid, and ischemic rat heart have been effectively restored by reconstituting mitochondria CL with thyroxin, acetyl-carnitine and antioxidant therapy to restore CL levels and CL-dependent protein functions.
In exploring Borg Metabolic X syndrome I went looking for why there is a decline in oxy phos ATP generation and consequent reliance on aerobic and anaerobic glycolysis to generate ATP. When fats are heated, hydrogenated, made into transfats or when omega-6 from cereals is eaten in excess of omega-3 this destroys the structure and function of the cell membranes and mitochondrial membranes. When these misshapen fats are incorporated into the cell membrane it becomes saturated, rigid, less flexible and unable to function properly. This in combination with the free radicals from chronic stress, industrial food, toxins, pollution leads to systemic cellular inflammation, insulin resistance and the breakdown of the intake mechanisms for getting both glucose into the cell and pyruvate into the mitochondria.
When cell voltage falls as a consequence of inadequate ATP production this throws off active ATP dependent transport, uptake receptors, membrane potential, function of ion gates (channels), pH differentials, nutrition and detoxification of the cell, and reduces the energy available for cell maintenance and repair. As the cell loses its metabolic intelligence the organism experiences an associated loss of consciousness, communication and sentience, whereby it falls out of bliss connection with Gaia and descends into an ever-deepening depleted or “needy” state.
Besides all the other factors in biological systems decline that leads to the fallen Borg condition, we must focus intently on the decreased quality of fatty acids and their disproportion in the diet as being instrumental to species degeneration; because of the consequent loss of Cardiolipin (L4CL) in the inner membrane of the mitochondria interferes with pyruvate uptake leading to the decline in oxy phos ATP generation. Vibrant cellular mitochondria respiration is the basis for good health. Depending on their energy demand organs are affected to differing degrees by impaired of mitochondrial function; the heart, the skeletal muscle cells, the brain and retina therefore show a much more pronounced response to mitochondrial insufficiency.
Thus we can say that Borg Metabolic X and its associated energy decline has a lot to do with cardiolipin loss in the inner membrane of the mitochondria. Insufficiency of this vital component and the reduced ATP underlie all degenerative disease and the mental-emotional-social decline of the species into undifferentiated “closed” Borg consciousness. The humanization process of specificity, complexity, depth, integration and “openness” are reduced due to this energy slump...even as human culture itself slowly evolves and technological progress powers ahead. The veneer of civilization thus props up the underlying metabolic-spiritual decline of the species, even as it is falling apart at its power-generating source. This loss of energy is ultimately dehumanizing both of the individual body, mind and soul, but also greatly undermines the overall progress of human evolution itself.
The symptoms of the Borg Metabolic X syndrome include: demineralization, HPA-hyperactivation, burnt-out adrenals, reduced thyroid, increased insulin resistance and collapsed mitochondria energy generation. This crippled condition forms the basis to the spiritual castration of populations into the uncreative slave populations (the sleep of sheep). It doesn’t take much imagination to see how the reduction in cellular energy production and the consequent loss of consciousness and Will to Live allows human predators and parasites to run riot over the globe. The runaway psychopathic control grid uses malevolent Nazi techniques to dehumanize society into the slave machine population. Once the ever-widening control grid has been set up over multiple generations via social-control techniques (a lot of which were developed by the Nazis in WWII) then we have to find ways to exit or transcend the cultural mind in order to save our soul, our bloodline and anything of true value in human life.
We see clearly how the net of species decline is set when we look at how hypothyroidism and low thyroid (thyroxin) levels ties into lower cellular respiration and the flip over to glycolysis associated with cancer, heart disease, diabetes, neuropathy and aging. The lower activity of the pyruvate carrier in mitochondria from aging and hypothyroidism may be ascribed to changes in the lipid domain surrounding the carrier molecule in the mitochondrial membrane. And how by reinstating our “normal” mitochondrial levels of Cardiolipin fatty acid we can increase our oxy phos ATP production, and in so doing increase cell voltage and thus reestablish the high energy levels needed for health and sovereignty. Plus raising the DHA levels of Cardiolipin also reinstates the healthy cell death (apoptosis) necessary to avoid cancerous growth. With inferior cardiolipin both the life and death processes of the cell are undermined.
We can observe how loss of thyroid function leads to the loss of pyruvate conversion into ATP by studying what happens with excessive thyroid activity. When rats are made hyperthyroid, hormone-mediated changes in the cardiolipin composition of the mitochondrial membranes occurs; in particular, the negatively charged phospholipids such as cardiolipin and phosphatidylserine were found to increase by more than 50%. Plus minor alterations were found in the pattern of fatty acids with an increase in the ratio 20:4 to 18:2 molar. These changes in the mitochondrial phospholipid composition alter the kinetic parameters of pyruvate transport in mitochondria. This in turn amplifies the activity of the pyruvate carrier and stimulates pyruvate-dependent oxygen uptake by 35-40% in mitochondria, essentially greatly raising cell metabolism. (Yet to be substantiated: if pyruvate cannot freely enter into the mitochondria due to inferior mitochondrial membranes, this must mean that glucose levels would build up in the cytosol…stimulating the enzymes for glycolysis…thus transferring the fuel for oxy phos ATP production over the anaerobic fermentation method that produces only 2 ATP, compared to the larger amount of 36-38 ATP by oxy phos, wasting 95% of the potential glucose energy.)
Studies indicate that rat cardiac mitochondrial oxygen consumption and the enzymatic activity of cytochrome oxidase decreased as the quantity of cardiolipin (L4CL) was reduced when the fatty acid composition of the diet was changed. A loss of CL content and alterations in its composition, along with CL peroxidation have been associated with mitochondrial dysfunction in a variety of pathological conditions, including ischemia, hypothyroidism, diabetes, aging, and heart disease. It is clear therefore that changes in the quantity, content and structure of CL occur in mitochondrial dysfunction forming the basis of metabolic dysfunction and degenerative disease.
Heart mitochondria from hypothyroid rats translocate pyruvate much more slowly and have a parallel decrease of the rate of pyruvate-dependent oxygen uptake from normal rats. IN FROM HYPOTHYROID RATS THE HEART MITOCHONDRIAL FATTY ACID PATTERN IN THE MITOCHONDRIAL MEMBRANES WAS ALTERED, SUGGESTING THAT CHANGES IN THE LIPID ENVIRONMENT WHICH SURROUNDS THE PYRUVATE CARRIER MOLECULE IN THE MITOCHONDRIAL MEMBRANE RESULTS IN THE DECREASED ACTIVITY OF THE PYRUVATE TRANSLOCATOR.
Mitochondrial dysfunction can occur when the amount of CL declines due to enhanced CL degradation (e.g., hydrolysis by endogenous phospholipases) or by the reduced synthesis of new CL, as a result of impaired enzyme function or the unavailability of CL precursors. Aging also reduces the rate of pyruvate transport in mitochondria (38%) and is associated with the parallel lowering in the rate of pyruvate-dependent oxygen uptake. This loss of efficiency can be attributed to the fact that heart aging significantly alters the mitochondrial lipid composition. These changes include total cholesterol increases (43%), the phospholipids decrease (15%) and the cholesterol/phospholipid molar ratio increases (68%). Among phospholipids, it is cardiolipin that shows the greatest alteration (28% decrease in aged rats), perhaps because of its extra vulnerability to oxidation.
Cardiolipin may be particularly susceptible to free radical peroxidation because of the abundance of double bonds in its structure and its close association with respiratory chain proteins, which are known to be a major source of reactive oxygen species (ROS) in the mitochondria. Oxidative injury of mitochondria is widely believed to play an important role in the mitochondrial decay and dysfunction seen in aging and may contribute to an age-associated decline in CL. Loss of CL and composition alterations due to aging was closely associated with decreased activity of the mitochondrial phosphate transporter, pyruvate carrier, adenine nucleotide transporter, cytochrome oxidase, and the Acetyl-l-carnitine transporter.
Acetyl-l-carnitine’s major function in the body is to help transport long-chain fatty acids so they can be used for eventual energy production. It also helps maintain levels of coenzyme A (acetyl-CoA), which is essential for a number of metabolic reactions. Acetyl-l-carnitine also has neuroprotective, cardioprotective, cytoprotective, antioxidant and anti-apoptotic activity. Vitamin C is required for the synthesis of the carnitine that is needed for this transport of fat into mitochondria, for conversion to energy. Lifelong intake of powerful antioxidants both supplemental and in the diet will help preserve cardiolipin levels and maintain energy generation as we age. *Remember, simply taking increased Omega-3 into a highly oxidizing, inflammatory, high blood sugar/glycating, fermenting, demineralized, hypothyroid/low-voltage body will only add high quality fuel to the process of putrification and decay.
Supplementation with L-carnitine and α-lipoic acid reduces CL losses and the age-related increase in free radicals (hydrogen peroxide) in heart mitochondria. Interestingly, acetyl-carnitine effects are limited to preservation of "normal" CL levels, and may involve improved mitochondrial fatty acid import and a preservation of cellular high-energy phosphate content needed for ATP. Not surprisingly treatment of aged rats with acetyl-L-carnitine reversed the age-associated decline in cardiolipin content. As the changes in cardiolipin content were correlated with changes in rates of pyruvate transport and oxidation, it is thought that acetyl-L-carnitine reverses the age-related decline in the mitochondrial pyruvate metabolism by restoring the normal cardiolipin content.
Acetyl L carnitine stimulates the electron transport as does caffeine and Coenzyme Q10. Kelp or iodine is necessary to keep up the thyroxin levels needed for Cardiolipin synthesis, for the thyroid hormone is a major regulator of mitochondrial biogenesis, respiratory function and lipid metabolism and has been shown to directly modulate CL content by influencing the activity of CL biosynthesis enzymes. Thyroxin induces new CL synthesis by increasing the activities of CL synthase and phosphatidylglycerol phosphate synthase, and promotes the remodeling of CL. Conversely, low thyroxin or hypothyroidism decreases the activities of CL synthase resulting in a significant loss of CL content and the functioning of CL-dependent protein, which in turn are restored by treatment with thyroid hormone. Thus the loss of CL and associated mitochondrial protein function in the aged, hypothyroid, and ischemic rat heart have been effectively restored by reconstituting mitochondria CL with thyroxin, acetyl-carnitine and antioxidant therapy to restore CL levels and CL-dependent protein functions.
Monday, July 4, 2011
THE HEART FAT OF MEME-BRAINS
We have learnt from Bruce Lipton and others that cell membranes are the crystalline semi-conducting brains of the cells that are the interface of communication flows between the inner and outer worlds. It is general knowledge that the human brain is composed of more than 60% structural fat and 50% of that is DHA Omega-3 fatty acid, so it is the most important fatty acid in the human brain. But what we didn’t know was the importance of the role of DHA in the composition of the cardiolipin inner membrane to the mitochondria.
In delving into the distress and degeneration of the human species, I came to the conclusion that the decline of humanity into masses of relatively uncreative automatons pushed around by a few tyrannical masters and the collapse of the humanization process itself to be caused by the disruption of energy generation in the cell’s mitochondrial power centers. It is apparent that this dysmetabolism arose due to lifestyle and diet changes from the Paleolithic period to the Neolithic age, which ultimately lead to the loss of wholebrain function and expedited the decline into our current exploitation/deprivation mode. That is, the metabolic fatigue at the heart of our lack of individuation and sovereignty can be largely attributed to the drop in cellular energy as the fatty acid composition of the mitochondrial inner membrane was changed by the agrarian diet and the increase in omega 6 from cereal consumption, at the expense of omega 3 rich hunter-gatherer diet.
We can begin to right this energy decline by reducing cereals in our diet and avoiding omega-6 polyunsaturated fatty acids, which are found in most types of vegetable oil (soybean, corn, safflower, canola etc…), while increasing the consumption of fish, fish oils and other omega-3 sources. By reconstituting the phospholipids foundations to the pyruvate transports in the mitochondrial membranes we can fire up the pure burning energy of oxy phos ATP. This along with taking cinnamon for overcoming insulin resistance and turmeric for inflammation throughout the day will stop us becoming a walking Petri dish for disease. Rectifying the cultural impact on our mitochondria will provide adequate energy for all active, flows, exchanges and movements and promote maximum metabolic efficiency. Essentially allowing us to biopsychically throw off 10,000 years of entrenched patriarchal rule by the sword. Speaking of cereal killer.
Interesting don't you think that the Paleolithic conserved the meme-brains of the mitochondria (which only carry female DNA), but when agriculture began (largely undertaken by females), then this lead to the alteration of our chemistry and brain function that ultimately lead to the subjugation of women, children, the weak, and the rape of Nature, the Earth and the Goddess. Over thousands of years we have made our meme-brains numb and dumb to the point where we wittingly harm ourselves without fear of the consequences. What was capable of the most supersensory reception of our EMF environment to the point of global scale telepathy, is now reduced to the mere knee jerk recognition of our robotic 3D world.
We are only as smart as our meme-brains are optimized as transmitters and receivers of the inner/outer continuum. By building perfected meme-brains we become transparent to God. The fact is our DNA can only respond to information arriving at the nucleus through the cell meme-brain, so quality membranes results in quality information transfer and consequently quality derepression and expression of DNA and RNA synthesis. Regeneration really is a process of re-generation once there is an improvement in communication, resources, environment and energy levels.
The reversion to less than human/humane social systems and behaviors has been greatly prolonged through the loss of physical, mental, spiritual strength associated with demineralization, cooked food, and cereal disruption of our mitochondrial function. Such that we have built a civilization that feeds on its own decomposition like a cancer. Knowing this, it is just a matter of education and the willingness to truly live to turn the Homo sapiens species back to divine communion and the laws of life. If we followed the laws of life then we wouldn't need to invest ourselves so fervently in disease. With smarts there is no need for the angel to be broken in order to fix it. It is time for us to follow the path of greatest compassion to invest in super-humanism and drop our addiction to disease. Once we work out the cultural processes that produce disease, we can learn to truly come alive.
As each of us unleashes our full cellular energy we can overcome the sadomasochistic patterns of dominance and submission that are holding the species back in a primitive, disempowered state and generating disease on all levels. With ideal ATP production to power our genius and enterprise we can begin to redeem our species karma, regenerate the earth and do the right-thing under universal law. We can even begin to know the true meaning of fun! Once full energy generation is achieved we can live a life of unity with Source, whereby all that is false and destructive falls away allowing the epigenetic de-repression of our humanity to begin.
In delving into the distress and degeneration of the human species, I came to the conclusion that the decline of humanity into masses of relatively uncreative automatons pushed around by a few tyrannical masters and the collapse of the humanization process itself to be caused by the disruption of energy generation in the cell’s mitochondrial power centers. It is apparent that this dysmetabolism arose due to lifestyle and diet changes from the Paleolithic period to the Neolithic age, which ultimately lead to the loss of wholebrain function and expedited the decline into our current exploitation/deprivation mode. That is, the metabolic fatigue at the heart of our lack of individuation and sovereignty can be largely attributed to the drop in cellular energy as the fatty acid composition of the mitochondrial inner membrane was changed by the agrarian diet and the increase in omega 6 from cereal consumption, at the expense of omega 3 rich hunter-gatherer diet.
We can begin to right this energy decline by reducing cereals in our diet and avoiding omega-6 polyunsaturated fatty acids, which are found in most types of vegetable oil (soybean, corn, safflower, canola etc…), while increasing the consumption of fish, fish oils and other omega-3 sources. By reconstituting the phospholipids foundations to the pyruvate transports in the mitochondrial membranes we can fire up the pure burning energy of oxy phos ATP. This along with taking cinnamon for overcoming insulin resistance and turmeric for inflammation throughout the day will stop us becoming a walking Petri dish for disease. Rectifying the cultural impact on our mitochondria will provide adequate energy for all active, flows, exchanges and movements and promote maximum metabolic efficiency. Essentially allowing us to biopsychically throw off 10,000 years of entrenched patriarchal rule by the sword. Speaking of cereal killer.
Interesting don't you think that the Paleolithic conserved the meme-brains of the mitochondria (which only carry female DNA), but when agriculture began (largely undertaken by females), then this lead to the alteration of our chemistry and brain function that ultimately lead to the subjugation of women, children, the weak, and the rape of Nature, the Earth and the Goddess. Over thousands of years we have made our meme-brains numb and dumb to the point where we wittingly harm ourselves without fear of the consequences. What was capable of the most supersensory reception of our EMF environment to the point of global scale telepathy, is now reduced to the mere knee jerk recognition of our robotic 3D world.
We are only as smart as our meme-brains are optimized as transmitters and receivers of the inner/outer continuum. By building perfected meme-brains we become transparent to God. The fact is our DNA can only respond to information arriving at the nucleus through the cell meme-brain, so quality membranes results in quality information transfer and consequently quality derepression and expression of DNA and RNA synthesis. Regeneration really is a process of re-generation once there is an improvement in communication, resources, environment and energy levels.
The reversion to less than human/humane social systems and behaviors has been greatly prolonged through the loss of physical, mental, spiritual strength associated with demineralization, cooked food, and cereal disruption of our mitochondrial function. Such that we have built a civilization that feeds on its own decomposition like a cancer. Knowing this, it is just a matter of education and the willingness to truly live to turn the Homo sapiens species back to divine communion and the laws of life. If we followed the laws of life then we wouldn't need to invest ourselves so fervently in disease. With smarts there is no need for the angel to be broken in order to fix it. It is time for us to follow the path of greatest compassion to invest in super-humanism and drop our addiction to disease. Once we work out the cultural processes that produce disease, we can learn to truly come alive.
As each of us unleashes our full cellular energy we can overcome the sadomasochistic patterns of dominance and submission that are holding the species back in a primitive, disempowered state and generating disease on all levels. With ideal ATP production to power our genius and enterprise we can begin to redeem our species karma, regenerate the earth and do the right-thing under universal law. We can even begin to know the true meaning of fun! Once full energy generation is achieved we can live a life of unity with Source, whereby all that is false and destructive falls away allowing the epigenetic de-repression of our humanity to begin.
Saturday, June 11, 2011
THE REAL AND THE MAZE
Like a stuck record our inner narrative is an outdated interpretation of past experience, which can be understood as an expression of our struggle with unresolved issues of identity, self worth, love and trust. I see atmospheric felt-senses, nostalgic qualia and elusive tinged memories of past figments of self as being part of the collective dream emerging from the subterranean zeitgiest of the species. Rather than own these figments as our own experience of past lives, which is a misleading personalization that stops inquiry, we should be using these impulses from the ocean of noesis for their seeds of transpersonal consciousness in divining a more direct route to the mystic civilization. For we know that the "Kingdom has come" and the "Kingdom lies within" and yet we forever miss the mark in bringing this Kingdom into manifestation, because we invariably personalize the signs and wrap them into the web of our small, limited story. However if we lived more from an archetypal viewpoint—in tune with the timeless continuum—we would question how these symbols and qualia could be weaved into the tapestry of High Art, which builds the bridge to the transcendent future.
One morning I was in an elaborate dream. A woman was leaving to catch a bus and was deciding to either take a taxi or to walk the distance to the bus station. In the dream I had the memory of having walked that route before, I looked at the map, but felt uneasy about exactly remembering how to get there. So apparently this is a dream of an inexact memory...and we can never know if I actually DID walk the route in a previous dream, or if I was only having a fake memory of a past dream event that never happened. Past life qualia are like this...the unconscious mind LOVES to show us just how magical and mysterious we are, but we miss the message when we cling to the personal story and the 3D.
To evolve we must Grok that “the imagination is unlimited” and it can dream up entire universes and any number of fake past lives to express its magical talent for infinity and meaning making. It is up to us to then interpret the “dream” in the most expedient fashion in establishing the High Art, which builds the bridge to the transcendent future. In this dream I had anxiety over my "prior knowledge" of the journey, but I also felt a deeply hidden impulse of “laissez faire” in recognizing that it was up to the Other to find their own way through the labyrinth...and that although my primary drive is to become a Map Maker and Pathfinder...I cannot walk the path for others, I must indeed focus on making my OWN journey one of High Art...for only in THIS way can the Kingdom come.
The barriers between the layers of my psyche started to significantly unravel on watching the emotionally healing TV series "Kyle XY" on netflicks. The firewalls between the compartmentalized levels of consciousness must be breached in order for integral consciousness and the whole human to come into effect. Soulful inquiry and communication about this process of emotional-psychic healing will allow us to navigate these opaque, unconscious waters without confounding the process with the “resistances” of collective schizo-paranoia that shatters the world into parts and separates us from the Self-synthesis of divine communion. Thus we must first become benign unto our-selves to exist in a benign world and thereby manifest the basic structures of undistorted universal life.
“It must be considered that there is nothing more difficult to carry out, nor more doubtful of success, nor more dangerous to handle, than to initiate a new order of things. For the reformer has enemies in all those who profit by the old order, and only lukewarm defenders in all those who would profit by the new order, this lukewarmness arising partly from fear of their adversaries, who have the laws in their favor; and partly from the incredulity of mankind, who do not truly believe in anything new until they have actual experience of it.” Machiavelli
Machiavelli was an astute observer of human nature...and it is this kind of screwed-if-you-do/screwed-if-you-don't cul-de-sac that we need to study and clearly elucidate in order to move on from underhanded Borg tactics to “cosmic genius unleashed from restraints.” The bottom line is that the Borg is UNSUSTAINABLE for it is against the life principle...thus the Borg and all its evil ways is on the way out. Therefore we had better soberly and sincerely align with what actually DOES WORK in the universe in order to survive and thrive. We must lighten up to the essence of our essential nature…that of adventure, exuberance, differentiation, inspiration and experimentation.
The facile pendulum of power is a game of conflict played out to entertain the brainstem of the masses and keep their eyes off the ultimate prize...personal sovereignty.
The negative pathway, which we might call “violence,” focuses more on the disenhancement of others in an effort to get on top. Eric Fromm points out that one’s frustration must be experienced as unjust or as a sign of rejection for it to lead to aggression. To free ourselves from the Borg’s path of violence we must stop rejecting our Self, and re-enchant our world by hacking open our psychic firewalls and knitting together our compartmentalized layers, to live in the truth of what does actually work for us. We must become “Real” by dropping the confusion, monotony and banality of utilitarian programming to invent, nurture, and make room for our unlimited Self that lies hidden behind the stone façade of the conditioned automaton. For the reign of peace on earth we all must stop the violence of self-rejection and become benign and Real unto our-selves.
Becoming Real: Defeating the Stories We Tell Ourselves That Hold Us Back by Gail, MD. Saltz and Gail Saltz. This is not your average self-help book! Gail artfully exposes our unconscious story-making that fatally influences our actions, happenstance and destiny.
One morning I was in an elaborate dream. A woman was leaving to catch a bus and was deciding to either take a taxi or to walk the distance to the bus station. In the dream I had the memory of having walked that route before, I looked at the map, but felt uneasy about exactly remembering how to get there. So apparently this is a dream of an inexact memory...and we can never know if I actually DID walk the route in a previous dream, or if I was only having a fake memory of a past dream event that never happened. Past life qualia are like this...the unconscious mind LOVES to show us just how magical and mysterious we are, but we miss the message when we cling to the personal story and the 3D.
To evolve we must Grok that “the imagination is unlimited” and it can dream up entire universes and any number of fake past lives to express its magical talent for infinity and meaning making. It is up to us to then interpret the “dream” in the most expedient fashion in establishing the High Art, which builds the bridge to the transcendent future. In this dream I had anxiety over my "prior knowledge" of the journey, but I also felt a deeply hidden impulse of “laissez faire” in recognizing that it was up to the Other to find their own way through the labyrinth...and that although my primary drive is to become a Map Maker and Pathfinder...I cannot walk the path for others, I must indeed focus on making my OWN journey one of High Art...for only in THIS way can the Kingdom come.
The barriers between the layers of my psyche started to significantly unravel on watching the emotionally healing TV series "Kyle XY" on netflicks. The firewalls between the compartmentalized levels of consciousness must be breached in order for integral consciousness and the whole human to come into effect. Soulful inquiry and communication about this process of emotional-psychic healing will allow us to navigate these opaque, unconscious waters without confounding the process with the “resistances” of collective schizo-paranoia that shatters the world into parts and separates us from the Self-synthesis of divine communion. Thus we must first become benign unto our-selves to exist in a benign world and thereby manifest the basic structures of undistorted universal life.
“It must be considered that there is nothing more difficult to carry out, nor more doubtful of success, nor more dangerous to handle, than to initiate a new order of things. For the reformer has enemies in all those who profit by the old order, and only lukewarm defenders in all those who would profit by the new order, this lukewarmness arising partly from fear of their adversaries, who have the laws in their favor; and partly from the incredulity of mankind, who do not truly believe in anything new until they have actual experience of it.” Machiavelli
Machiavelli was an astute observer of human nature...and it is this kind of screwed-if-you-do/screwed-if-you-don't cul-de-sac that we need to study and clearly elucidate in order to move on from underhanded Borg tactics to “cosmic genius unleashed from restraints.” The bottom line is that the Borg is UNSUSTAINABLE for it is against the life principle...thus the Borg and all its evil ways is on the way out. Therefore we had better soberly and sincerely align with what actually DOES WORK in the universe in order to survive and thrive. We must lighten up to the essence of our essential nature…that of adventure, exuberance, differentiation, inspiration and experimentation.
The facile pendulum of power is a game of conflict played out to entertain the brainstem of the masses and keep their eyes off the ultimate prize...personal sovereignty.
The negative pathway, which we might call “violence,” focuses more on the disenhancement of others in an effort to get on top. Eric Fromm points out that one’s frustration must be experienced as unjust or as a sign of rejection for it to lead to aggression. To free ourselves from the Borg’s path of violence we must stop rejecting our Self, and re-enchant our world by hacking open our psychic firewalls and knitting together our compartmentalized layers, to live in the truth of what does actually work for us. We must become “Real” by dropping the confusion, monotony and banality of utilitarian programming to invent, nurture, and make room for our unlimited Self that lies hidden behind the stone façade of the conditioned automaton. For the reign of peace on earth we all must stop the violence of self-rejection and become benign and Real unto our-selves.
Becoming Real: Defeating the Stories We Tell Ourselves That Hold Us Back by Gail, MD. Saltz and Gail Saltz. This is not your average self-help book! Gail artfully exposes our unconscious story-making that fatally influences our actions, happenstance and destiny.
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