Monday, July 9, 2012

VITAMIN C ~ (L-ascorbic acid)


THE ANTI-STRESS HORMONE 

You can get rid of pathogens using Vitamin C...at anti-cancer rates of 8-10gms.

Phylogenetic Implications of Vitamin C Synthesis

As plants and animals emerged from aquatic environments onto the land around 400-300 million years ago the challenge of terrestrial life was to acquire certain marine micronutrients, including iodine, selenium, zinc, copper, manganese, iron, etc. To replace these marine minerals life learned to produce other endogenous antioxidants such as Vitamin C, polyfenols, Beta carotene, bioflavonoids, Vitamin E etc. Thus the vast majority of plants and animals on earth are able to convert glucose into ascorbic acid through a sequence of four enzymatic steps. The glucose needed to produce ascorbate in mammals is extracted from glycogen in the liver. While in reptiles and most birds it is produced in the kidneys. However due to a genetic mutation that occurred millions years ago humans and higher apes do not manufacture Vitamin C. Since tarsiers also cannot make vitamin C, this implies the mutation had already occurred, and thus must have occurred between 63 to 58 Mya. Guinea pigs, certain bats, and certain birds, some fish and higher apes have also lost the ability to manufacture Vitamin C internally.

When higher primates lost the ability to synthesize ascorbate they lost the homeostatic feedback mechanism which increases ascorbate synthesis under the influence of external and internal stresses.  The cause of this phenomenon is that the final enzyme in the synthetic process, L-gulonolactone oxidase, cannot be produced due to a defective gene for the enzyme. This mutation has not been lethal because vitamin C has been abundant in their food sources. For example most monkeys consume vitamin C in amounts 10 to 20 times higher than the RDA. On the other hand, with animals that still produce their own endogenous Vitamin C: cats make up to 2800 mg a day, rabbits up to 15,820 mg, goats up to 13,300 mg and as much as 100,000 mg daily when faced with life-threatening disease, trauma, or stress. The human body needs around 12,000 mg/day, but doesn't produce Vitamin C. Uric acid and ascorbate are both strong reducing agents (antioxidants). The loss of the humanity’s ability to synthesize ascorbate parallels the loss of the ability to break down uric acid. This observation has led scientists to speculate that in higher primates, uric acid may have taken over some of the functions of ascorbate.

Bill Sardi in “The New Truth About Vitamins and Minerals” says that a 160 lb mountain goat makes about 13 grams of Vitamin C a day, and more when under stress. Vitamin C is an anti-stress vitamin and our need for it varies with our level of physical or emotional stress. Stress causes the adrenal glands to signal the release of sugars and fats into the blood stream to prepare for a response to danger. In most other animals but apes, fruit bats and guinea pigs these sugars are converted to Vitamin C in the liver. Sardi suggests that if humans also manufactured Vitamin C, we would be immune to degenerative disease and our lifespan would be more like 144-216 years.

Vitamin C is available in many forms, and according to Linus Pauling natural and synthetic L-ascorbic acid are chemically identical. Linus Pauling says that the true and best form of vitamin C is L-ascorbic Acid (C6H8O6). When taking Vitamin C there needs to be up to 70% bioflavonoids taken along with it to increase assimilation, utilization and prolong the ascorbic acid’s effects. A. Dr. Albert Szent-Gyorgyi was the first to discover the bioflavonoid effect during his research work on vitamin C, when he determined that another substance that he called vitamin-P (bioflavonoids) lead to improvement in capillary permeability.

Bioflavonoids (phenols or flavonoids) are the natural pigments, giving fruit, leaves, flowers, and other plant parts their vibrant colors. Bioflavonoids help protect the plant from these harmful UV rays and neutralize the free radicals-unstable molecules with an unpaired electron-which they produce. Bioflavonoids are abundant in virtually all plant foods. However, the greatest dietary sources of bioflavonoids are green tea, onions, apples, grapes, roots, herbs, cacao, Propolis, citrus fruits, berries, Red Bell Peppers, Cabbage Family, Rose Hips, Pomegranates, acai, goji berries, mangosteen, noni, Pycnogenol, quercetin, grape-seed extract, green tea. Cinnamon extract contains bioflavonoids called proanthocyanidins that are very similar to the proanthocyanidins contained in grape seeds. Bioflavonoids work with the other antioxidants to offer synergistic protection from free radicals, aging, toxic chemicals, and metabolic waste products. Bioflavonoids help replenish the body’s own antioxidants, including glutathione peroxidase, coenzyme Q10, alpha-lipoic acid, and super oxide dismutase (SOD). Together with dietary antioxidants, these endogenous antioxidants help to protect the body against the thousands of free-radical hits that each cell experiences daily.

Vitamin C is a common enzymatic cofactor in mammals used in the synthesis of collagen. It acts as an electron donor for three enzymes participating in the synthesis of collagen. If vitamin C is missing, then the collagen synthesized in its absence is weak, resulting in the entire body losing its structural integrity. The free radical scavenging and collagen building properties of Vitamin C are important to upright walking hominids and full sovereign brain utilization through spinal health—for symptoms of vitamin C deficiency reduce spinal integrity resulting in scoliosis, lordosis spinal curvature and impaired cognition. The central nervous system has the highest concentrations of Vitamin C, where it influences the function of neurotransmitters such as dopamine, norephinephrine, serotonin, NMDA and glutamate. Vitamin C’s role in the synthesis of the neurotransmitters has a stimulating effect, fosters alertness, and plays an important regulatory role in long-term memory and learning.

The nucleus accumbens and hippocampus have high concentrations of Vitamin C and it is known to play a vital role in dopamine production as well. The secretion of the stimulating neurotransmitter glutamate by the brain induces the release of ascorbic acid into the extracellular space. The binding of ascorbic acid to the glutamate receptor could mean that ascorbic acid holds great potential in treating disease related to excitotoxic glutamate damage. That is, the ascorbic acid and glutamate are inversely related so theoretically, high concentration of ascorbic acid in the diet could inhibit glutamate release, lessening the risk of excitotoxic damage. It also protects endorphins from being broken down prematurely, which elevates mood. Mega-dose Vitamin C is used during opiate withdrawal as it fills the opiate receptors and greatly reduces withdrawal symptoms. In the aging brain there are reduced levels of ascorbic acid and glutathione peroxidase, hence elevated levels of free radicals and lipid peroxidation. As we age, we produce less of the transferrin transport protein that normally binds free iron. As a result, older individuals have higher levels of rust-susceptible free iron within their tissues, including brain.

Vitamin C is required for the synthesis of carnitine, needed for the transport of fat into mitochondria, for conversion to energy. Bruce N. Ames, professor of molecular and cell biology at UC Berkeley, fed older rats acetyl-L-carnitine and alpha-lipoic acid. They found that the combination of the two supplements effectively reduce aging by up-regulating the mitochondria, rejuvenating and energizing cells. Both spatial and temporal memory improved, and there was reduced oxidative damage to RNA in the hippocampus, the brain's memory area. Besides liposomal Vitamin C, it is advisable for those undergoing kundalini awakening or stress to take L-carnitine and alpha-lipoic supplements as well as adopt a low glycemic diet.

Vitamin C is needed for bile production, as an antimutagenic and may also protect from lead poisoning by inhibiting intestinal absorption or enhancing urinary excretion of lead. Heavy metal ions interfere with enzyme reactions, reduce T cell function and make colloids lose their ability to hold water. Powerful cross-linkers (free radical-tissue agers) are the metallic ions of cadmium, aluminum, copper, titanium, lead and iron. Vitamin C helps keep these heavy metals in solution so they can be eliminated. Heavy metal damage due to lack of vitamin C from a cooked diet (and other factors of course) is suspect in senility, Alzheimer's , mental illness, criminal violence and ADD. Vitamin C removes excess copper from the body and supports the adrenal glands.

It is important to take antioxidants together, such as vitamin E (as D- alpha-tocopherol) and alpha-lipoic acid, to regenerate the reduced form of the vitamin. In terms of its antioxidant activity, vitamin C and E interact in such a way as to restore each others active antioxidant state. Vitamin C scavenges oxygen radicals in the aqueous phase and vitamin E protects the lipid membrane layer. Alpha-lipoic acid acts powerfully to keep the ascorbate and tocopherol in the reduced state (antioxidant state). When you take Vitamin C tablets make sure they are not the chewable type or you will lose tooth enamel. I am using “Now C-1000 with Bioflavonoids.”

   Mineral Salt Vitamin C
Ascorbic acid and its sodium, potassium, and calcium salts are commonly used as antioxidant food additives. These compounds are water-soluble and thus cannot protect fats from oxidation: For this purpose, the fat-soluble esters of ascorbic acid with long-chain fatty acids (ascorbyl palmitate or ascorbyl stearate) can be used as food antioxidants. Ascorbate terminates free radical reactions by serving as a stable (electron + proton) donor. The oxidized forms of ascorbate are relatively unreactive, and do not cause cellular damage, and can be converted back to ascorbate by cellular enzymes. Mineral ascorbates are a non-acidic pH neutral form of Vitamin C that provides the great benefits of Vitamin C without upsetting the stomach and digestive system. Mineral salts of ascorbic acid (Sodium ascorbate and Calcium ascorbate, Magnesium ascorbate, Potassium Ascorbate) are buffered and therefore, less acidic to the stomach than ascorbic acid. When magnesium ascorbate, calcium ascorbate and potassium ascorbate are taken in a glass of water there is an immediate increased sense of well being in the belly, reduced brain fog and sense of internal cleansing...as the mineral ascorbates are a good electron donor (reduce oxidation/inflammation) in relieving acidic-low oxygen-high pathogen conditions.

NATURAL VITAMIN C

The richest natural sources of Vitamin C are the Kakadu plum and the camu camu fruit.

Kakadu Plum—(Terminalia ferdinandiana) the gubinge, billygoat plum or murunga grows natively across the Top End of Northern Australia. This wild olive looking fruit contains 3000mg of vitamin C per 100g of fruit - over 50 times the concentration found in oranges. The anti-oxidant ((ORAC) activity was four or five times higher than in blueberries, in fact there is no plant in the world that has the same level of vitamin C, anti-oxidants and bioactives. The Kakadu Plum contains phytochemicals such as gallic acid which is antibacterial, antiviral and antifungal; and ellagic acid which has anti-carcinogenic effects. http://www.kakaduplum.com.au/ — Freeze dried powder

Camu Camu—Is a fruit containing the highest documented quantity of natural vitamin C on earth. Camu Camu's vitamin C content has been recorded at 500,000 ppm.  Compare that to orange which provides 500 to 4,000 ppm (parts per million) of vitamin C, or Acerola which provides up to 172,000 ppm.

Goji BerriesLycium  or Wolfberries belong to the nightshade (Solonaceae) family and contain 50 times more Vitamin C than oranges. It is a vegetarian form of protein, packed with nineteen amino acids including all eight essential for life, rich in vitamin A and a good source of vitamin C and polysaccharides that help strengthening immune system. Goji berries possess over 20 trace minerals and vitamins including zinc, iron, phosphorus, riboflavin (B2), vitamin E as well as carotenoids, including beta-carotene and zeaxanthin, which is highly beneficial for eyes.

Amla (Amalaki)—The Indian gooseberry, is one of the fruits in the most widely used Ayurvedic herbal formula – Triphala. It is considered a general panacea for almost all imbalances and described as containing 20 times the amount of vitamin C to be found in an orange. The fruit contained 482.14 units of superoxide dismutase/g fresh weight. As one of the highest vitamin C sources in nature,  amla fruit is antiaging, antidiabetic and immune enhancing. The powder of the dried amla fruit is an effective remedy of hyperacidity, ulcers, blood cleansing, inhibits platelets aggregation, lowers cholesterol levels. Amla is a longevity tonic, which stops premature graying or hair-loss, encourages nail and hair growth, and improves eyesight.

Rose Hips—Are a valuable source of vitamin C, like Amla they contain 20 times more vitamin C than oranges. Overripe hips are sweet, but have lost much of their vitamin C. Rosehips are also full of bioflavonoids, associated with fruit pigment that increase the absorption and biological effectiveness of vitamin C.

Moringa Oleifera—The dried and powdered leaves of the tree provide 7x the vitamin C of oranges. Be aware that the skins and seeds/kernels of plants contain the most amount of antioxidants…for example mango peel and kernel has antioxidant levels that are 20-40 times higher than the flesh itself. One study showed that pomegranate peel gave the maximum antioxidant activity due to the presence of its high polyphenolic content. At a concentration of 60 ppm pomegranate peel powder reduced fat oxidation by 65% in an in vitro assay.

Pinebark Extract—Pycnogenol helps potentiate vitamin C and other antioxidant activity. I also recommend including other antioxidants such as vitamin E and beta-carotene, along with vitamin C, for their protective ability. Moreover, many of the B vitamins are important as cell fuel, as are several key minerals and CoEnzyme QIO.

Grapeseed Extract— Grape Seed Extract is a Super Antioxidant - 20-50 times more powerful than Vitamin C, E, & Beta Carotene.  Grape Seed Extract is an antiallergenic, antihistamine, anti-inflammatory, antioxidant, and it strengthens blood vessels, improves skin and aids in circulation. Grape Seed Extract contains proanthocyanidins bioflavonoids which help strengthen and protect cell membranes from oxidative damage caused by free radicals. Resveratrol, a powerful antioxidant found in grape skins, grape seed extract, D-glucarate, a cellular detoxifier, calcium and ellagic acid all seem to work in harmony together to protect against skin cancer. Supplemental resveratrol has been shown to reduce skin cancer tumors by up to 98 percent, to stop production of leukemia cells. cancer cells have a lot of defective pathways and they are very vulnerable if you target those pathways. The same is not true of healthy cells. Grape seed extract triggers DNA damage in the cancer cells (via increased reactive oxygen species) and inhibits the necessary repair mechanism used by the cells to regenerate and multiply. The Grape Seed polyphenols support brain health, improve cognition and lower the risk of dementia. Catechins help reduce allergic responses by inhibiting enzymes involved in the formation of histamine. GSE & MSM are a great combination for healthy hair. Citrus Bioflavonoids (Vitamin P) enhance the usefulness of Grape Seed Extract by increasing capillary strength and regulating absorption.

How to Live Longer And Feel Better by Linus Pauling
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Liposomal Encapsulated Vitamin C

Liposomal-C uses ascorbic acid powder and lecithin for a lipid delivery system, by encasing nanoparticles of nutrients (herbs, too) in a phospholipid membrane or “liposome,” allowing safe passage through the gastrointestinal tract without degradation. Thereby avoiding the destructive forces of the gut so that Liposomal-C can be directly absorbed into the blood stream. “Lypo-Spheric Lecithin-Vitamin C” permits 90% ascorbic acid to get into cells, because cell walls are made of fats and normal Vitamin C is water soluble, while regular vitamin C is only absorbed around 19%. Vitamin C encased in liposomes is claimed to be far more absorbed approaching or exceeding intravenous Vitamin C, but it is less expensive than IV C treatments. The traditional form of Vitamin C, in tablet or capsule, is subject to a host of factors that can oxidize it, neutralize it, adulterate it, and even expel it before it ever gets to the cells that need it. The Liposomal-C because of their nano size and composition, provide the perfect transport system.

The best known phospholipid is phosphatidylcholine (aka lecithin). Because it's structure allows it to be a interface of water-lipid environments, there are two main functions of phospholipids: A key component of the cell's lipid bilayer, and emulsification. Foods rich in phosphatidylcholine include: egg yolks, liver, soybeans, wheat germ, and peanuts. Lecithin represents a similar phospholipid substance to our cell walls so the liposomal material is assimilated by the phospholipid-craving cells that need phosphatidylcholine and the Vitamin C. Vitamin C filled liposomes disperse in water or beverage and quickly navigate through the digestive system, requiring no digestive activity prior to assimilation. They rapidly absorb in the small intestine and are transported intact throughout the bloodstream to release the powerful, non-degraded Vitamin C for use throughout the body as the liposomal material is metabolized by the cells requiring repair.

Mix solutions of Vitamin C and Sunflower Lecithin (or nonGM soy lecithin) and place the two solutions, together in either an ultrasonic cleaner. This system works to encapsulate 70% of the Vitamin C. This Mini-Ultrasonic-Cleaner on ebay can be run quietly for 30 minutes without pause. 30W/50W Professional Mini Ultrasonic Cleaner For Jewelry Glasses Circuit Board

http://www.ebay.com/itm/30W-50W-Professional-Mini-Ultrasonic-Cleaner-For-Jewelry-Glasses-Circuit-Board-/180914418963?pt=LH_DefaultDomain_0&hash=item2a1f56f513

• Soak and dissolve 3 level tbls of “Sunflower Lecithin” in 1 cup of distilled water.
• Dissolve 1 level tbls of Pharmaceutical grade Vitamin C powder in half a cup of distilled water. Then mix in a bullet mixer or blender for 30 minutes OR…
• Pour both solutions together in the ultrasonic cleaner bowl and turn unit on. With the lid open use a plastic straw to slowly stir the contents. This will take about 30 minutes or so. When done you will have a mix that is about the color of milk with no foam.
• If the 15g vitamin C powder (one tbls) batch is taken over two days then this is about 7-8g Vitamin C per day. This is the RDA for  your average human or goat.
• Therapeutic dose can be 1/3 cup Liposomal-C in 1/3 cabbage cider or another high enzyme liquid…3 times a day. This cuts inflammation, oxidation, pain…
Buffered vitamin C powder will NOT go into a liposomal state. It looks OK for a little while, then it separates.

Love Raw Foods Sunflower Lecithin - Raw 16 Oz.

www.swansonvitamins.com  —1 lb each of Swanson Premium 100% Pure Vitamin C Powder

http://www.nuscicorp.com/products   —Excellent bulk supplements, also on
www.amazon.com

Video on how to make Liposomal Encapsulated Vitamin C

KUNDALINI AND LIPOSOMAL ANTIOXIDANTS

Due to the increased appetite for fruit-sugar, plus the increased biophoton light, free radicals, metabolism and energy generation etc... a kundalini awakening can quicken the onset of insulin resistance, glycation and the oxidation of cell membranes. Particularly noticable is the degrading of the skin collagen in the later years of a kundalini awakening. You may notice a sense of the blood sugar pooling in the blood and feeding pathogens rather than getting into the cells. You may also notice a shortness of breath, in that the oxygen is not getting around the body due to glycated hemoglobin. This is especially apparent if one has awakened without the support of family or community, and when the cortisol produced by high stress levels has exacerbated this oxidative/insulin resistance process. This peroxidization of our fatty cell membranes and caramelization of our protein structures can be avoided by keeping up a supernutrition level of reducing factors that supply electrons to the body and sop up the excess free radicals as they occur...thereby preventing damage to the mitochondrial cellular energy production itself.

You can see from the above paragraph on glycation why it is vital to avoid grains and carbohydrates, and heat damaged or processsed fats during an awakening. Generally the more stressed we are the more careful we have to be to not include cooked carbs, fats or transfats in our diet, and to increase our antioxidant intake. Especially important as super-antioxidants are the wild weeds, herbs, fruits and trees...as things in the wild usually have a higher antioxidant load than human cultivated and hybrid plants. The nervous system can exhibit convulsions, spastic ticks, kriyas (automatic movements), burning, crawling, fog, clamping pressure etc...during peak kundalini due in part to the oxidative breakdown of the myelin sheaths. Increasing the body's glutathione, alpha lipoic acid and Vitamin C is essential to avoid the difficult symptoms of nervous system overload. In fact Debbie M actually got rid of her left-brain freeze (clamp, crab, pizza dough) by taking 8g Liposomal Vitamin C per day. Besides the antioxidant and glutathione preserving effects of the Vitamin C she also benefited from the myelin and cell membrane repair afforded by the lecithin in the recipe. After getting success with Liposomal Vitamin C she went on to make Liposomal Glutathione as well. During a kundalini awakening or acute stress it is advisable to supplement with Vitamin C up to 4-8g per day.

1 comment:

  1. I haven't read everything about Vitamin C in such a detail. Thank you Jana for writing this informative article. I love knowing the benefits of fruits and about their vitamins and minerals. By thinking positive about what I'm eating or drinking, it makes me feel good.

    Best Regards,
    Mantis Hugo
    Gooseberry Juice

    ReplyDelete