Glucose oxidation in the brain requires certain cofactor micronutrients. For instance, forms of several B vitamins, including thiamin, riboflavin, niacin, and pantothenic acid, as well as the compound lipoic acid, are utilized in reactions that completely metabolize glucose to carbon dioxide and water. Additionally, the nutritionally essential minerals, magnesium, iron, and manganese are required for the complete metabolism of glucose; these micronutrients are utilized as cofactors, substrates, or components of enzymes in glycolysis and the citric acid cycle. Moreover, generation of cellular energy in the form of ATP by the electron transport chain requires the vitamins, riboflavin and niacin; iron contained in iron-sulfur clusters; and the endogenously synthesized compound, coenzyme Q10.
Taking cinnamon, L-Aspartic Acid, gymnema, jambul, chromium, vanadium and alpha lipoic acid along with carbohydrate meals can help blood sugar to enter the cells and thereby aid in energy generation. The minerals chromium and vanadium help the insulin transport sugar to the cells. Gymnema sylvestre is a herb known to affect the glucose/insulin system favorably at the pancreatic level and significantly lowers cholesterol. Bilberry lowers elevated blood sugar levels. Riboflavin (B2) serves as a precursor to flavin adenine dinucleotide, a coenzyme involved in the energy-producing mitochondrial electron-transport chain.
INSULIN RESISTANCE—Metabolic X syndrome and obesity are strongly correlated with insulin resistance, glucose intolerance, stress and a sedentary lifestyle, i.e., low physical activity and excess caloric intake. Insulin resistance reduces the uptake of glucose into the liver and muscle cells for use as fuel or for storage and interferes with thyroid function. The restoration of insulin sensitivity is necessary for the function of SNS mediated thermogenesis. Chromium, niacin, zinc, manganese along with GLA, fiber, vitamin C and B complex help renew insulin sensitivity. Fructose (fruit sugar) rather than sucrose (sugar) is better for stimulating thermogenesis as fructose does not increase insulin levels
CHROMIUM—The essential trace element chromium regulates the body’s blood sugar levels by facilitating the uptake of glucose into cells. It increases the activity of insulin, thereby reducing the amount of insulin required to control blood sugar. Chromium is also a component of glucose tolerance factor (GTF), and has been shown to increase number of insulin receptors, enhance receptor binding, and potentiate insulin action. Since chromium reduces insulin resistance, this leads to wide-ranging effects including lowering high blood pressure and abnormal blood lipids in addition to lowering blood sugar and reducing obesity.
CINNAMON—As our cells become increasingly resistant to insulin’s efforts to facilitate glucose transport from the bloodstream into the cells, the pancreas tries to compensate by producing more and more insulin. This can lead to the dangerous condition of hyperinsulinemia, or excessive insulin levels in the blood. Some researchers have begun to focus their interest on the possible role of this condition in the development of cancer. Cinnamon contains procyanidins (type A), a class of bioflavonoids that mimic the functions of insulin in important ways, maintaining healthy blood sugar levels and a healthy lipid profile, as well as other aspects of good health. At the highest cinnamon concentration used, tumor proliferation was reduced by about 50% compared with the untreated control cells. A regular dose is around 1 heaping teaspoon (3.5 g) of whole-cinnamon powder per day. Cinnamon can be added to ground flax-chia seed sprinkle, and Chai.
ALKALINE BUFFERING—Studies show that Chronic Fatigue sufferers have raised levels of blood lactate, indicating suboptimal aerobic ATP production that can lead to fatigue and muscle aches. Supplementing with Krebs’ cycle amino acid precursors and intermediates to stimulate ATP production, while buffering lactic acid. Extra calcium phosphate in the diet will help counter the lactic acid generated by exercise, suboptimal aerobic ATP production and pathological bacteria. Calphonite, is liquid Calcium-Phosphorous. Calcium and magnesium combine with lactic acid, neutralizing the negative effect of excess lactic acid, normalizing pH, and normalizing breathing, emotional disturbances, and restoring the ill health.
Removing the obstructions to optimal aerobic ATP production is just as important as building up the structures and biochemistry for cellular respiration. For the excess build up of metabolic byproducts like hydrogen ions, and lactic acid interferes with ATP generation and nerve and muscle function. By buffering lactic acid and excess hydrogen ions we can relieve muscle soreness, brain fatigue and improve sports performance. Intracellular buffers include phosphates, carnosine and bicarbonates. While bicarbonate is the main blood buffer, phosphates and carnosine buffer acids in the muscles. Phosphate supplements increase 2,3-diphosphoglycerate (2,3-DPG) in the red blood cells speeding the release of oxygen from hemoglobin. (Hydrogen peroxide also serves this purpose). Phosphate supplements include: Sodium Phosphate and Potassium Phosphate, Magnesium ascorbyl phosphate.
CREATINE—ATP has three phosphate molecules bonded to an adenosine molecule. When one of the bonds connecting these phosphate molecules is broken through a process known as hydrolysis, a great deal of energy is created. It is this breaking of bonds between molecules that produces all of the energy utilized by the body. Furthermore phosphate helps in the phosphorylation of creatine to creatine phosphate to reform ATP and thereby raise energy. Creatine is used for the resynthesis of ATP. Dietary creatine is absorbed readily and makes its way to the muscles, where it combines with the phosphates which are always lying around to make phosphocreatine. If you have a substantial amount of phosphocreatine in your muscle cells, you should be able to generate a lot of ATP in a very short period of time. Creatine phosphate donates its phosphate to ADP, instantly creating the ATP needed to make muscles work. As creatine phosphate helps to create ATP, it consumes hydrogen ions released by the lactic acid which can build up in muscle cells during intense physical effort. This "buffering" action helps to delay fatigue that otherwise occurs when excess hydrogen ions interfere with muscle contractions. Plus creatine phosphate transports the ATP out of the mitochondria to your muscles, thus creatine can improve performance. Since the cell's concentration of creatine phosphate is three to five times higher than that of ATP, creatine phosphate functions as a cellular energy reservoir. A maintenance dose of creatine monohydrate generally amounts to three grams per day. NOW Foods Creatine Powder, 2.2 Pounds by Now Foods.
CARNOSINE—Carnosine is a combination of two amino acids, beta-alanine and L-histidine. Carnosine is a super anti-aging supplement not only due to it being the premier anti-glycating agent, but it also protects neurons against reactive and cytotoxic protein carbonyl species associated with normal aging. Carnosine is a powerful antioxidant, act as a neuro-transmitter, improves blood flow to brain, speeds up cell replacement. In its role as an intracellular buffer Carnosine helps maintain optimal pH balance by soaking up hydrogen ions (H+) that are released at an accelerated rate during exercise. It is the released H+ from lactic acid that causes muscular performance problems, but H+ ions are also being released at a rapid rate when you break down the high energy compound ATP during exercise. Carnosine is a powerful precursor in generating enzymes necessary for making the powerful vasodilator nitric oxide. When you ingest carnosine intact, most of it is broken down in the gastrointestinal (GI) tract into its constituent amino acids, beta-alanine and histidine.
BETA-ALANINE—By supplementing with the powerful intracellular buffer beta-alanine, we can specifically and dramatically increase carnosine levels by 42-65%. By boosting carnosine concentrations, with beta-alanine, our type 2 muscle fibers can soak up more H+ and stay in an optimal pH range to maintain maximal strength and endurance throughout your workout session and bring on new muscle gains, lean body mass, power and muscular endurance. The greatest natural dietary sources of beta-alanine are believed to be obtained through ingesting the beta-alanine containing dipeptides: carnosine, anserine and balenine, found in protein rich foods such as chicken, beef, pork and fish.
EXERCISE—Exercise increases mitochondrial number and efficiency leading to greater ATP production and better oxygenation of the tissues and draining of lymphatic toxins. Regular aerobic exercise also increases the total number of red blood cells in the body, facilitating the transport of oxygen. Highly trained athletes are also more efficient at converting lactate to glucose and therefore have lower lactate levels. Training also improves the ability of muscles to use fats during exercise, preserving intramuscular glycogen. Without an adequate blood sugar level, (> 2.5-3 mmol/l) brain activity is impaired. It is interesting that it is the “transport” of glucose into the brain that becomes rate-limiting at low blood glucose levels, and that exercise increases the glucose transporter molecules! Plus physical training reduces insulin resistance, enhances the efficiency of glycogen production and storage in the liver and increases glucose output from the liver. Vigorous exercise at least once a week was found to reduce the risk of type 2 diabetes by 33%. Melatonin also increases muscle and liver glycogen content.
Weight Training Reverses Almost 40 years of Aging—in Six Months. Restores Youthful Genetic Footprint to Mitochondria. www.cbass.com/Mitochondria.htm
http://www.johnberardi.com/articles/training/gettinginshape.htm —Training The Energy Systems
LIGHT—Red and near-infrared light can affect cell membrane permeability and aid the production of ATP thereby providing the cell with more energy which in turn means the cell is in optimum condition to play it's part in a natural healing process. The forest is our genetic home…foliated canopies deplete the blue and red portions of the spectrum and allowed more green and near-infrared light to reach the forest floor.
EMF—"The nature of the mind is to make coherence of the world.” Bruce Lipton PhD. Each tissue, indeed each atom has a given harmonic…which when tuned into sympathetic resonance with surrounding life and matter creates coherent frequencies that switches on DNA in special ways, in the same way that a symphony comes “together” or not. Certain EMF devises like Gene Koonce’s Vibe Machine, the Rife's machines, Wilhelm Reich’s orgone machine, Tesla’s coils seems to give a jolt to the ATP cell energy manufacture, by correcting the body's intracellular frequency to allow the body to make ATP more efficiently, or detoxify heavy metals from the body. Voltage plus harmonics equals health. Theories of resonance in health have been proposed by Lakhovsky, Priore, Szent-Györgyi, John Worrell Keely (svpvril.com), Walter Russell and then more recently by Ray Tomes, Emoto and Oschman. Bioelectromagnetic Healing: A Rationale for its Use by Thomas Valone.
BREATHING—Shallow breathing reduces the oxygen content of the blood and too much carbon dioxide makes the heart beat faster to deliver what little oxygen there is to the brain. When cells are oxygen deprived we use the lactic acid pathway to produce energy just as normal healthy people do after prolonged exercise. This lactic acid resulting from the breathing pattern of an A-type personality can worsen mineral status through fostering overly acid conditions in the blood. The more hurried you are, the tenser you become, and the worse the breathing, so notice your breathing, deepen and slow its pace down. This messes up the pH differentials that run the body’s chemiosmotic energy generating system ultimately ending in mutation of DNA (cancer). To become sovereign, that is an invincible independent monarch, besides exercise we also need to engage in conscious breathing and up our oxygen levels to make the most of our mitochondrial energy production.